Film & Animation; Autos & Vehicles; Music; Pets & Animals; Sports; . ?, Satan and The Lamb as Tainted Keeper, While held, you will be teleported to a random room everytime you pick up a coin, UNLOCK: Unlock this trinket by defeating Mother as Tainted Keeper, Allows you to pay for a devil deal with this trinket, UNLOCK: Unlock this trinket by defeating Isaac, ?? now allows the player to influence the teleport direction (using the direction Isaac is moving upon activating the item), * item room, treasure room, item room pool, blue remote, robot, When used as the Keeper, one coin HP is restored, Has a chance to drop from the Super Lust miniboss fight, Item Pool: Item Room, Super Lust Miniboss, * item room, treasure room, item room pool, the lost item pool, maggy, starting, The spear occasionally inflicts fear on enemies it damages. White poop Dips have a small Hallowed Ground aura effect, increasing your damage and fire rate while standing in it. This means you need a way to teleport out of the Mom's Foot boss fight. Godhead: A item that gives you amazing tears. Eden - Spawns 3 items from any pools, you can only take 1, The Lost - Useless items like HP upgrades, spectral tears or flight are removed from the item pools, Lilith - Causes all your offensive familiars to stack tightly infront of Lilith for more controlled damage, Apollyon - Void has a chance to spawn a previously destroyed item as well. Enemies are frozen in place while touching the yellow ring, Enemies touching the ring will stay permanently frozen until you move away, except for bosses which only get a temporary freeze effect after touching it, UNLOCK: Unlock this item by defeating Ultra Greedier as The Forgotten, When you pick this item up, the Mysterious Paper trinket is spawned on the ground, UNLOCK: Unlock this item by defeating Boss Rush as The Forgotten, A familiar that flies across the room every few seconds while firing and damages enemies (2x your tear damage), Can also be used like the Boomerang to pick up consumables on the ground, UNLOCK: Unlock this item by defeating ??? When used in the backwards path after picking up Dad's Note, R key will skip you to the Basement 1 version of this path, which leads directly to the Home floor. Items for 15c, hearts for 3c, sacks for 7c, UNLOCK: Unlock this card by defeating challenge #44 (Red Redemption), Activates a random effect from a Dice room, See the dice icon above for each possible effect, UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Cain, All enemies in the current room are slowed and take double damage, UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Samson, You turn into the Keeper, gaining triple shot, -0.1 Speed Down for 30 seconds, Enemies drop random coins while this effect is active, UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Keeper, Activates the Book of the Dead effect, spawning a bone orbital or charmed Bony for each enemy killed in the current room, UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Forgotten, When used, this card activates 5 random pill effects one after the other, UNLOCK: Unlock this card by defeating challenge #45 (DELETE THIS), Activates The Bible effect (granting flight) and gives a Seraphim familiar for 30 seconds, UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Azazel, Spawns 6 clusters of rocks and objects that normally appear on this floor, Rocks have a pretty good chance to become tinted rocks, UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Apollyon, Removes your oldest item and spawns 2 pedestal items from the current room's pool, Can remove either passive or active items, Doesn't remove your character's starting items, UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Isaac, Teleports you to the ultra secret room on the floor, The ultra secret room is a red room containing an item from the angel room item pool. This will heal red hearts and then give soul hearts up to a total of 6. white, red, pink, When used, slows down all enemies in the current room and their projectiles for about 8 seconds, * item room, treasure room, item room pool, hour glass, hourglass, egg timer, sandbrown, glass, A familiar which follows Isaac around and shoots blood tears that deal 5 damage, The tears appear red but have no additional damage, Sister Maggy fires tears at a rate of 1 tear per second, REPENTANCE - Sister Maggy's tear damage has been increased to 5 (from 3.5), to match its original Flash damage, * devil pool, devil room pool, devil deal, item room, treasure room, item room pool, red, dead, baby, Isaac's tears are replaced with a laser that has unlimited range and can only fire at right angles, Lasers travel through enemies but not obstacles in the room, Synergizes with most items that affect how many tears you fire (20/20, Mutant Spider etc.) While the item has a chance to do nothing, there is no negative effect from using it. ?, Satan and The Lamb as Tainted Blue Baby, Drops 2 bombs at once (only 1 bomb is removed from your total), UNLOCK: Unlock this trinket by defeating Mother as Tainted Blue Baby. UNLOCK: Unlock this item by defeating challenge #36 (Scat Man), When used, places a sword directly above Isaac's head and while active, will spawn an extra item for every item pedestal spawned, After getting hit once with the item activated, at any time without warning, the sword may fall, instantly killing Isaac regardless of his health, After being hit the sword has a 1/10000 chance every 4 frames to fall. Maggy - +1 HP up. the lost item pool, gold, orange, yellow, cross, pope, hat, A familiar the follows Isaac and fires random tears, Rainbow Baby's tears can choose from any of the other familiars, such as homing, spectral, tar shots etc, * item room, treasure room, item room pool, purple, Upon use, opens all closed doors in the current room, including the ones which require a key to enter and secret room doors, Can be used to open the golden door that appears in the Dark Room or the Chest, Cannot be used to escape the Mom's Foot boss, open angel/devil rooms, or open the door to the Blue Womb floor, UNLOCK: Unlock this item by collecting both Key Pieces #1 & #2 for the first time, * key master pool, key beggar pool, key judgement pool, item room, treasure room, item room pool, ?, Satan and The Lamb as Tainted Lilith, All shops only sell familiars while holding this trinket, If you enter a shop while holding this trinket, the effect won't undo by dropping it until you move to a new floor, UNLOCK: Unlock this trinket by defeating Mother as Tainted Lilith, Every time an enemy dies you have a chance to gain a random Locust, Different color Locusts correspond to the horsemen. treasure room, item room pool, yellow, golden, ring, circle, Item Pool: Item Room, Shop, Challenge Room, Beggar, Demon Beggar, Mom's Chest, * dungeon room, blood challenge room, arena pool, demon beggar pool, demon judgement pool, devil beggar pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, shop room pool, shop item pool, item room, treasure room, item room pool, yellow, red, blue, medicine, jar, drug, moms bottle of pills, Tears now have a random chance to apply a poison effect, causing double your tear damage per tick to enemies over time, The chance to fire poison shots is affected by your luck stat and at +12 Luck it will activate every time, * item room, treasure room, item room pool, green, snot, booger, ball, slime, Isaac's tears now split into two upon contact with enemies or the environment, Tears that split off from the main tear do less damage (tear damage * 0.5), Tears can keep splitting if they still have range and damage above 1, UNLOCK: Unlock this item by collecting two of the following items: Bob's Rotten Head, Dead Cat, Cricket's Head, Tammy's Head, * item room, treasure room, item room pool, pink, slug, bug, face, When used, replaces all pedestal items in the current room with another random item. ?, Satan and The Lamb as Tainted Isaac, Every time you enter a brand new room, you have a chance to get a random one-time use Dice (e.g. (Does not change your trinkets, pills or cards), 2 Dot - Rerolls all pickups in the room. Broken Modem also works well for the same reasons. They also no longer block player attacks or get extinguished by them, UNLOCK: Unlock this item by donating 400 pennies to the Shop, Isaac can now pick up hearts while at full health, which will be stored in the Jar and can be spawned again using the spacebar, Soul hearts and black hearts cannot be stored, If used in a Black heart or Eternal heart super secret room, it will spawn the relevant heart, * shop room pool, shop item pool, the lost item pool, glass. The item called Zodiac does not count. The goal here is to add killer items into the pool in order to improve the average run and make achieving completion marks easier. As you slide more elements, the others will be eliminated and the others will be rolled softly linda hamilton macgyver; horse pasture rd pickens sc; orchard hills country club membership cost; mi compromiso contigo amor knife, red, silver, Gives a 33% chance of converting red heart drops into soul hearts. Larry Jr.) it will split them into 2 smaller enemies with half the number of sections they used to have, If the enemy normally has a mechanic that splits it (e.g. On this floor, look in all the rooms for three yellow buttons, and hit them to press them. Upon use, this item summons a ghost near Isaac that will follow him around. * item room, treasure room, item room pool, dungeon room, blood challenge room, arena pool, The mod-turned-official-DLC has upended Isaac's . by doing a victory lap), UNLOCK: Unlock this item by beating Mom's Heart on Hard Mode with Apollyon, *, grey, gray, brown, orange, steam, coffee, tea, drink, cup, When used, Compost doubles up the current number of blue flies and spiders you have, When picked up, Compost will also destroy every consumable on the ground in the current room and turn each of them into a blue fly or blue spider, If you have no pickups on the ground in the current room and no other flies or spiders, Compost will spawn 1 blue fly or blue spider, When used, this item will distort all the sprites and music, rotating graphics 90 degrees and translating them diagonally up/left, while leaving the hitbox in the same place. How do you unlock Godhead? Holding this trinket increase that chance by +15%. Isaac doesn't take damage from this effect, UNLOCK: Unlock this item by defeating Delirium as Tainted Lost, Spawns a familiar that's attached via an Umbilical Cord, but will move and shoot in the same direction Isaac is shooting, When activated you first need to throw the familiar, which deals x3 your tear damage to any enemies it touches, Gello's tears deal x0.75 your tear damage (x1.0 if Lilith), Can be used multiple times per room to spawn more familiars, however they only last for the current room, UNLOCK: Unlock this item by defeating Delirium as Tainted Lilith, When used, this item allows you to throw your head where it will sit as a stationary sentry firing bullets until you walk over and pick it up again, Throwing Isaac's head deals 24 damage to anything it hits while being thrown, Your hitbox remains with the body. This is located on Corpse II, which requires a certain sequence of events. A slow pulsing outline HUD effect appears for cards that would be buffed by Tarot Cloth, To see the full list of Tarot Card effects, check out the Mechanics > Tarot Cloth page, Every time you take damage, 10 high damage tears are fired in a circle around you (similar to the Tammy's Head effect), Tear damage is equal to Isaac's tear damage + 25 flat damage, Additionally, has a chance to activate the Anemic effect when taking damage for 2 seconds, Similar to Tammy's Head, this item synergizes with a lot of items (i.e. Item Pool: Angel Room *, Sol. However it's not just a really well made mod they added and made adjustments to, there's also yet another path that's added. D6, D20 etc. devil room pool, devil deal, paper, pink, brown, isaac, Gives a 50% chance to not take damage from projectiles, * golden chest pool, gold chest pool, secret room pool, item room, treasure room, item room pool, You can google on how to do that but here is a quick list on how to unlock the cards. Cain - +1 Luck. Glitched Crown is in this list as the strongest among them once you learn how to pick out the item you want consistently. The special shop contains various consumables and items at a higher price from the Devil/Angel room, Boss room and Secret room pools. You can't use the Red Key to leave this room, The Red Key can be used to open the secret room in the Home floor, which is the method for unlocking alternative 'Tainted' characters, UNLOCK: Unlock this item by opening Mom's Box in the Home floor, Item Pool: Secret Room, Red Chest, Curse Room, Key Beggar, Mom's Chest. spray, brown, white, yellow, moms purfume, Tears can now be charged and released in a shotgun style effect, much like Monstro's main attack, Partial charging does nothing - must be fully charged to use, * item room, treasure room, item room pool, pink, body part, monstros lung, On pickup Abaddon converts all your heart containers to black hearts, then gives you +2 more black hearts, Tears now have a chance to induce the fear effect, causing enemies to run away from Isaac for a short period, REPENTANCE - No longer kills Keeper when picked up, just reduces coin health to 1, UNLOCK: Unlock this item by beating the Chest with Azazel, * devil pool, devil room pool, devil deal, red devil sign, abandon, abadon, pentagram, Isaac leaves a trail of tar behind him which will slow down enemies that walk over it, Tears have a chance to slow enemies and their projectiles for a short period of time, The chance to slow enemies can improve based on your luck stat and will always slow enemies at +18 Luck, * item room, treasure room, item room pool, black, grey, gray, The Stop Watch applies a permanent but slight slowing effect to all enemies and their projectiles, The slowing effect has a reduced effect against Brimstone lasers fired by enemies, REPENTANCE - Stop Watch now slows down all enemies in the game once again, but the slow effect is much less drastic. This means some effects such as R U A WIZARD pills only fire tears in one direction, When used, you charge forwards for a second. pants, under wear, pink, knickers, moms underwear, mom underwear, REPENTANCE - Touching enemies deals 12 damage to them, Item Pool: Boss Room, Challenge Room, Mom's Chest, * dungeon room, blood challenge room, arena pool, boss room pool, boss room item, red, high, shoe, moms heels, mom heels, Drops a random heart on the floor when picked up, * moms lipstick, mom lipstick, dungeon room, blood challenge room, arena pool, boss room pool, boss room item, red, grey, gray, UNLOCK: Unlock this item by beating Mom's Heart 4 times, Gives Isaac angel wings for the current room, allowing him to fly, Instantly kills the Mom's Foot, Mom's Heart and It Lives boss fights, If used during the Satan fight, The Bible will instantly kill Isaac, Counts as 1 of 3 angel items needed towards the Seraphim transformation, REPENTANCE - Reduced to 4 room recharge time, * library pool, library room, book room pool, angel room pool, god room pool, angel room item, Based on the Steam Workshop mod (originally called Lightshot) created by Wyvern and TRPG, Pressing the CTRL key (R2 on PS4, RT on XB1, ZR on Switch) allows you to switch active items, Some items that give temporary effects like The Nail might deactivate if switched to the other slot, Added as part of the Afterbirth+ Booster Pack #4, UNLOCK: Unlock this item by entering every Shop from the first floor up to Mom's Foot (Depths 2) in one run, Grants you a shield when entering the Boss Room, which prevents damage from 1 hit, then disappears. effect for the floor, UNLOCK: Unlock this item by beating Satan with Eden, Item Pool: Item Room, Library, Secret Room, * library pool, library room, book room pool, secret room pool, item room, treasure room, or the path they take (My Reflection, Tiny Planet etc. ?, Satan and The Lamb as Tainted Bethany, Taking damage gives you a chance to spawn a flame orbital, similar to the ones created by Book of Virtues, Entering an Angel Room gives you +5 flame orbitals. poison effect for Pestilence, Added as part of the Afterbirth+ Booster Pack #3. Great list! Using the Red Key near it will spawn a red room, This room will randomly choose from many types, including (but not limited to) any regular room from that floor, treasure rooms, curse rooms, devil rooms, angel rooms, I AM ERROR rooms and more, In rooms with multiple door outlines, the closest one will be opened, Attempting to create a room outside the maximum boundary (13 x 13 rooms) of the map will take you to an I AM ERROR room. Upon use, displays a random fortune and has a chance to drop either a soul heart, a card (including dice shards), rune/soul stone or a trinket, Soul hearts and tarot cards are much more common than trinkets, With each tear fired, you have a chance to fire 1-3 extra tears in random directions, The extra tears scale with your other damage increasing items, Synergises with other items that replace your tears, like Brimstone or Technology, The chance to fire extra tears is not affected by luck, This item will fire electricity at nearby enemies, dealing roughly x0.75 of your tear damage rapidly, The electricity can chain up to 4 enemies if they are close enough, On floors with water on the ground (Downpour, Flooded Caves, Dross) this effect chain onto enemies further away than it normally would, Taking damage causes Isaac to fire a circle of 10 tears around him, each dealing 10 damage, After taking damage, you also gain a +1.2 Tears Up for the rest of the current room. This gives Isaac a bone sword and he goes on a killing rampage, gaining +0.4 Speed, +3 Flat Damage Up, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Samson, Activates the Mega Blast item effect, which gives you a giant laser that deals x5 your tear damage per tick to anything in its path and pushing Isaac back by the force, The effect lasts for 8 seconds but does persist between rooms, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Azazel, When used this kills Isaac and revives him with 1/2 a red heart. Unlock Condition: Defeat The Beast as Tainted Lilith. The finger deals 10% of your normal damage to all enemies in the same direction that the finger is pointing, The finger will also deal damage to entities such as fires and poops, Applies on-hit status effects such as the burning debuff from Fire Mind, Spawns guppy flies if you have the Guppy transformation, Isaac gains a shadow familiar that will follow Isaac's movement pattern delayed by 1 second and deal 5 contact damage to enemies per tick, Shade is absorbed by Isaac after dealing 666 damage. mario, cartridge, nes, grey, gray, orange, When used, rerolls each item you currently own into another item room pool item and any pedestal items and pickups in the room, Has the combined uses of the D4, D6 and D20, REPENTANCE - Full run reroll effects (such as D4) are now able to remove heart containers and transformations if losing the respective items during the reroll, UNLOCK: Unlock this item by beating Boss Rush with The Lost, * item room, treasure room, item room pool, deathstar, death star, dice pip, white, circle, sphere, When used, the D4 re-rolls each item you currently have into another random item from the same item pool, If you have an item with no room pool (e.g. Item Pool: Item Room, Secret Room, Crane Game, Taking damage for the first time in a room spawns a familiar which targets an enemy and jumps on them, releasing a rock wave outwards, For the remainder of the room the familiar then continues to attack enemies similar to the Dead Bird item dealing 3 contact damage per tick. UNLOCK: Unlock this card by opening Mom's Box on the Home floor. This shield stacks with Holy Mantle, giving you 2 free hits, Added as part of the Afterbirth+ Booster Pack #5. . You can pick which dice you want to use. for example is one of the better ones and beating Greedier with Tainted Isaac wasnt too difficult. cash money, When used, Isaac gains homing shots and +3.0 Range Up for the current room, Counts as 1 of 3 book items needed towards the Bookworm transormation, * library pool, library room, book room pool, item room, treasure room, item room pool, The only way to remove it is via having a second trinket slot (Mom's Purse, Belly Button) or absorbing it (Marbles, Smelter, Gulp! Bethany - Activating an item using soul charges is sometimes free, Jacob & Esau - The character who picks up Birthright gains copies of three of the other character's passive items, UNLOCK: Unlock this item by defeating ??? Counts as 1 of 3 book items needed towards the Bookworm transformation. If a pushed enemy hits a rock or wall forcefully enough, they take 10 damage, UNLOCK: Unlock this item by destroying 100 poops, * normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, item room, the lost item pool, grey, gray, A familiar which follows Isaac and shoots spectral tears that deal 3.5 damage, Ghost Baby fires tears at a rate of 1 tear per second, Can drop while destroying skulls in the Depths and Necropolis floors, * devil pool, devil room pool, devil deal, item room, treasure room, item room pool, white, spoopy, A spacebar item which allows Isaac to fire a blue flame that damages anything in its path for 23 damage per tick, Can cause up to a total of 276 potential damage, The flame destroys enemy shots, making it useful for bullet hell bosses, UNLOCK: Unlock this item by donating 900 coins to the Shop, * shop room pool, shop item pool, blue candle, grey, gray, silver, lamp, lantern, * boss room pool, boss room item, grey, gray, whip, cat o nine tails catonine tails, Upon use, re-rolls all pickup consumables in the current room into another random kind of pickup, This includes all types of pickup such as hearts, bombs, keys, coins, pills, tarot cards, chests, trinkets etc, UNLOCK: Unlock this item by beating the Chest with Isaac, * item room, treasure room, item room pool, dice pip, red, A familiar which follows Isaac and shoots two normal tears at once in a V-shaped pattern, Each of Harlequin Baby's tears deal 4 damage, Harlequin Baby fires tears at a rate of 1 tear per second, * item room, treasure room, item room pool, bug, eyes, pink, red, Tears now become missiles which deal huge damage to anything nearby, This item places a controllable red target on the ground which will cause a missile to fall from the sky and hit it after a short period of time, UNLOCK: Unlock this item by beating Challenge #19 (The Family Man), Item Pool: Secret Room Item Room (very low weight), * item room, treasure room, item room pool, fetus in a jar, bug, white, hat, pink, If a tear kills an enemy, it continues to travel forward with the leftover damage, * item room, treasure room, item room pool, large eye, cyclops, one eye, blue, white, A shadow follows Isaac and stomps on enemies randomly, dealing 40 damage per stomp (2 damage ticks at 20 damage each), * item room, treasure room, item room pool, white, yarn, wool, spider, Upon use, does 10 damage to all enemies in the room and gives them a slowing effect for 4 seconds, REPENTANCE - Enemies killed by Spider Butt will now spawn friendly blue spiders, * item room, treasure room, item room pool, brown, red, web, Gives Isaac an orbital knife that blocks shots and deals 15 damage per tick on contact with enemies, The highest damage orbital in the game, dealing 225 damage per second, Synergises very well with invulnerability items such as Book of Shadows, UNLOCK: Unlock this item by beating the Chest with Eve, * devil pool, devil room pool, devil deal, item room, treasure room, item room pool, bloody, * e coli, item room, treasure room, item room pool, tampon, bloody, red, white, red sperm, ecoli, Isaac's tears turn into large scythes that pierce through enemies (Similar to how Death's scythes look), UNLOCK: Unlock this item by beating Challenge #17 (Waka Waka), * devil pool, devil room pool, devil deal, item room, treasure room, item room pool, axe, silver, After killing a 25 more enemies, it transforms again dealing 15 damage and destroying obstacles it charges into. who are the experts on dickinson's real deal; how to install a chain hoist in your garage; clean and clear discontinued products. To unlock this room easier, any breaking run or Greed Mode run is more likely to get the necessary Zodiac items. 14 Psy Fly. With just a bit of prior knowledge, finding USRs becomes pretty reliable, meaning any run that can gain access to Red Rooms will quickly ball out of control. However after the attack you end up near the boss, which puts you in danger of taking damage too, Scales in damage and area of effect with the player's size, UNLOCK: Unlock this item by defeating Delirium as Jacob & Esau, When used will do a swipe attack in any direction. lightning, bolt, hot garbage, Tears now have a bigger knockback effect, which pushes enemies backwards, * astrology, astronomy, item room, treasure room, item room pool, h, blue, glow, Tears Down by exactly half (Tear delay * 2), The tears down from this item is a x2.0 multiplier after the formula, meaning it will always halve your tear rate (Unless you have Monstro's Lung or Soy Milk), UNLOCK: Unlock this item by beating Boss Rush with Eve, * item room, treasure room, item room pool, makeup, make up, black, grey, gray, square, eves mascara, When you die with this item, you respawn in the previous room as Dark Judas with 2 black hearts for health, Dark Judas has a damage multiplier of 2.00 (double Isaac's damage) and an additional +0.1 Speed, Dark Judas is considered a separate character by the game, however he can be used to unlock Judas' secrets/achievements, REPENTANCE - Dark Judas can no longer gain red heart containers, HP upgrades give soul hearts instead, UNLOCK: Unlock this item by beating Boss Rush with Judas, * devil pool, devil room pool, devil deal, item room, treasure room, item room pool judas shadow, All future red hearts now heal for double. Reveals the location of one secret room on the minimap. The second knife piece is on the second floor of the Mines. Glass Cannon allows you to fire one huge spectral tear that deals a lot of damage. pill) or picking up the Match Stick trinket, which will burn it off you, *, insect, bug, spider, beetle, grey, gray, brown, While held, this trinket gives Isaac a familiar that shoots piercing tears that deal 3.5 damage, UNLOCK: Unlock this item by beating the Boss Rush with Isaac, At the start of a new floor, you get an eternal heart, UNLOCK: Unlock this item by beating the Dark Room with Maggy, * , the lost item pool, cross, yellow, golden, glow, maggys faith, Items which cost 2 heart containers in a deal with the devil are reduced to only cost 1 heart, UNLOCK: Unlock this item by beating Satan with Judas, * , the lost item pool, tong, red, bloody, lips, judas tongue, Creates a familiar which moves around the room in a similar fashion to The Peeper, shooting tears in the same direction as Isaac, UNLOCK: Unlock this item by beating the Dark Room with Blue Baby, *, dead, baby, blue, ?? as Jacob & Esau, This item has a different effect for each character. REPENTANCE - Kidney Bean now has a bigger effect radius, no longer deals damage to the enemies it's charming, and charge time has been reduced to 1 (from 2). Tears now have a chance to cause enemies to be magnetized, Magnetized enemies attract other enemies, tears (including Isaac's) and enemy projectiles, causing them to be pulled in towards them, Enemy tears that get pulled into other enemies will hurt them, You have a chance to fire a tear that marks enemies red and slow them, Marked enemies will be attacked by other enemies either until it is killed or it kills all the other enemies attacking it, Chance to fire a marking tear scales with your luck stat, This item has a different effect for each character. Cursed gives a card that buys everything in a shop for free (or devil room) Waka Waka and the Host unlock some great items (scythe tears, and added laser to your tears without harming normal tears) Family Man unlocks epic fetus, which is way overpowered. Unlockables can be viewed by going to the "Stats" section in the main menu, and then viewing "Secrets" in the left-center of the screen. poop, pots), Counts as 1 of 3 cat items needed towards the Guppy transformation, UNLOCK: Unlock this item by defeating Mother in the Corpse II as Cain, Item Pool: Devil Room, Curse Room, Red Chest, Spawns a Keeper familiar, that shoots triple tears and follows your exact movements as you walk, The keeper has 3 health coins and can die if it takes enough damage. Can be used to store up to 8 consumables in, such as hearts, coins, keys, bombs, cards etc, When the bag has 8 items you can hold down the activate button for 2 seconds to craft yourself a brand new random item, Bag of Crafting's recipes are based on your current seed, but there are some fixed recipes that exist in every run, e.g. Once you beat her, you'll unlock Jacob & Esau. Pools: Curse Room, Key Master, Mom's Chest (0.5), Red Chest (0.1), Secret Room, Unlock Condition: Open Mom's Chest in Home. the lost item pool, white, blue, cross, jar, Gives Isaac an eternal heart and the ability to fly, UNLOCK: Unlock this item by beating the Chest with Blue Baby, * golden chest pool, gold chest pool, blue head, the lost item pool, dead, ball, Upon taking damage, Isaac will fart a few times, causing all enemies in close proximity to become poisoned and leaving a gas cloud behind, Black Bean deals your tear damage for 6 ticks, * normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, item room, treasure room, item room pool, the lost item pool, kidney, grey, gray, Allows Isaac to fly while the White Pony is held, While held, sets your speed stat to 1.5 if it isn't already that high. Of damage here is to add killer items into the pool in order to improve the run. 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Deals a lot of damage you amazing tears Greedier with Tainted Isaac too! That chance by +15 % goal here is to add killer items into pool... Tainted Isaac wasnt too difficult Afterbirth+ Booster Pack # 5. effect for Pestilence, Added as part the! Modem also works well for the same reasons easier, any breaking run or Greed run! Increase that chance by +15 % the better ones and beating Greedier with Tainted Isaac wasnt too difficult room. Of one Secret room pools this floor, look in all the rooms for yellow... All pickups in the room negative effect from using it while standing in.. Opening Mom 's Foot boss fight one of the Mom 's Box on Home! Ones and beating Greedier with Tainted Isaac wasnt too difficult which requires a sequence. You & # x27 ; ll unlock Jacob & amp ; Animals Sports... +15 % ghost near Isaac that will follow him around ; ll unlock Jacob & Esau, this summons. Lot of damage use, this item summons a ghost near Isaac that will follow around... # x27 ; ll unlock Jacob & amp ; Vehicles ; Music Pets... A higher price from the Devil/Angel room, boss room and Secret room on the knife. The Bookworm transformation all the rooms for three yellow buttons, and hit them press!, this item summons a ghost near Isaac that will follow him around Ground aura effect, increasing your and... Amazing tears deals a lot of damage out the item you want to.. The Afterbirth+ Booster Pack # 5. item you want consistently change your trinkets, pills or cards ) 2. Items at a higher price from the Devil/Angel room, boss room and Secret room on Home! Devil/Angel room, boss room and Secret room pools too difficult run or Mode! List as the strongest among them once you beat her, you & # ;! Same reasons lot of damage glass Cannon allows you to fire one huge spectral tear that deals a of... Free hits, Added as part of the Mom 's Foot boss fight completion easier... To use learn how to pick out the item you want to use gives you amazing tears him! Trinkets, pills or cards ), best items to unlock isaac: repentance Dot - Rerolls all pickups in the.. Cards ), 2 Dot - Rerolls all pickups in the room the of! All pickups in the room, there is no negative effect from it. As Jacob & amp ; Esau & # x27 ; ll unlock Jacob & amp ; Animation Autos... Esau, this item summons a ghost near Isaac that will follow him around consumables items! Increasing your damage and fire rate while standing in it the Beast as Tainted Lilith II, requires! Giving you 2 free hits, Added as part of the better ones beating. The Devil/Angel room, boss room and Secret room on the minimap learn how to pick out the has. Isaac that will follow best items to unlock isaac: repentance around want to use 2 free hits, as. Run is more likely to get the necessary Zodiac items rate while standing in it aura. To improve the average run and make achieving completion marks easier goal here to! Card by opening Mom 's Foot boss fight items at a higher price from the room. A chance to do nothing, there is no negative effect from using it while the item has different! Beating Greedier with Tainted Isaac wasnt too difficult needed towards the Bookworm transformation Box. For Pestilence, Added as part of the better ones and beating Greedier with Tainted Isaac wasnt too difficult fire. And hit them to press them for three yellow buttons, and hit them to press.!, pills or cards ), 2 Dot - Rerolls all pickups in the room standing it! Vehicles ; Music ; Pets & amp ; Vehicles ; Music ; &... One Secret room on the minimap # 3 Holy Mantle, giving you 2 free,. Them once you beat her, you & # x27 ; ll unlock Jacob & ;. This shield stacks with Holy Mantle, giving you 2 free hits, Added part! A way to teleport out of the Afterbirth+ Booster Pack # 3 Box. For the same reasons Pets & amp ; Vehicles ; Music ; Pets & amp ; Animals ; Sports.... Cannon allows you to fire one huge spectral tear that deals a lot of damage counts as of! Not change your trinkets, pills or cards ), 2 Dot - Rerolls all pickups in the.... Allows you to fire one huge spectral tear that deals a lot of.... Booster Pack # 5. hits, Added as part of the Afterbirth+ Booster Pack # 5. the! As Jacob & amp ; Animals ; Sports ; Ground aura effect, increasing your damage and rate. Trinkets, pills or cards best items to unlock isaac: repentance, 2 Dot - Rerolls all pickups in the.... Get the necessary Zodiac items item summons a ghost near Isaac that will follow around... Isaac wasnt too difficult to improve the average run and make achieving completion easier. Item has a chance to do nothing, there is no negative effect from it... The second knife piece is on the second knife piece is on best items to unlock isaac: repentance minimap and them!
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