Optometry 2000;71:147-64.. View abstract. 2012;96(5):1223S-1233S. Similarly, other studies show that higher dietary intakes ofzeaxanthin and lutein along with other natural antioxidants, includingvitamin C,beta-caroteneandvitamin E, are associated with a significantly decreased risk of cataract formation. Chung HY, Rasmussen HM, Johnson EJ. B., Xu, X. R., Zou, Z. Y., and Lin, X. M. Lutein and zeaxanthin intake and the risk of age-related macular degeneration: a systematic review and meta-analysis. View abstract. San Giovanni, J. P., Chew, E. Y., Clemons, T. E., Ferris, F. L., III, Gensler, G., Lindblad, A. S., Milton, R. C., Seddon, J. M., and Sperduto, R. D. The relationship of dietary carotenoid and vitamin A, E, and C intake with age-related macular degeneration in a case-control study: AREDS Report No. J.Nutr. Carotenoids are a group of naturally occurring pigments that are largely responsible for the red, yellow, and orange color of fruits and vegetables and some animals. Previous studies have found that lutein helps bolster the skins natural antioxidant system and protect against sun damage, and reduces the risk of age-related 1995;36(12):2531-2541. Cho, E., Hankinson, S. E., Rosner, B., Willett, W. C., and Colditz, G. A. Eur J Clin Nutr 2007;61:1167-73. While the research is still in its early stages, taking lutein three times weekly for up to two years has been shown to improve vision in older people who already have cataracts. Supplementation with carotenoids, omega-3 fatty acids, and vitamin E has a positive effect on the symptoms and progression of Alzheimer's disease. Novel phytonutrient contributors to antioxidant protection against cardiovascular disease. View abstract. Dherani, M., Murthy, G. V., Gupta, S. K., Young, I. S., Maraini, G., Camparini, M., Price, G. M., John, N., Chakravarthy, U., and Fletcher, A. E. Blood levels of vitamin C, carotenoids and retinol are inversely associated with cataract in a North Indian population. Am.J.Clin.Nutr. Long-term Outcomes of Adding Lutein/Zeaxanthin and ?-3 Fatty Acids to the AREDS Supplements on Age-Related Macular Degeneration Progression: AREDS2 Report 28. WebLutein & Zeaxanthin Eye Health Supplement for Adults - Delicious Vegan Eye Vitamins Lutein and Zeaxanthin Gummies - Zeaxanthin Plus Lutein 20mg for Vision Clarity Dry Eye Relief and Blue Light Support. Density of the human crystalline lens is related to the macular pigment carotenoids, lutein and zeaxanthin. 7-15-2001;391(2):160-164. Eczema is a skin condition that affects around 1530% of children and 210% of adults ().Scientists have found the cause of eczema may be mostly genetic. Am J Clin Nutr 1997;66:366-72. Nutrient intake and cataract extraction in women: a prospective study. View abstract. J Nutr 2004;134:2387-94. 2006;84(5):971-974. Evans JR, Lawrenson JG. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. Zeimer, M. B., Kromer, I., Spital, G., Lommatzsch, A., and Pauleikhoff, D. Macular telangiectasia: patterns of distribution of macular pigment and response to supplementation. View abstract. Asian Pac J Cancer Prev. Beatty, S., Murray, I. J., Henson, D. B., Carden, D., Koh, H., and Boulton, M. E. Macular pigment and risk for age-related macular degeneration in subjects from a Northern European population. Connolly, E. E., Beatty, S., Loughman, J., Howard, A. N., Louw, M. S., and Nolan, J. M. Supplementation with all three macular carotenoids: response, stability, and safety. 80 mg of zinc. Arch.Biochem.Biophys. Invest Ophthalmol Vis Sci. Some animal studies show evidence that lutein offers significant protection against light-induced skin damage, such as signs of aging and potentially skin cancer. B., Russell, R. M., and Yeum, K. J. Supplementation with lutein or lutein plus green tea extracts does not change oxidative stress in adequately nourished older adults. View abstract. Zhou Y, Wang T, Meng Q, Zhai S. Association of carotenoids with risk of gastric cancer: a meta-analysis. View abstract. View abstract. An eye disorder in premature infants that can lead to blindness (retinopathy of prematurity). Bahrami, H., Melia, M., and Dagnelie, G. Lutein supplementation in retinitis pigmentosa: PC-based vision assessment in a randomized double-masked placebo-controlled clinical trial [NCT00029289]. Naylor CD, O'Rourke K, Detsky AS, Baker JP. Palombo, P., Fabrizi, G., Ruocco, V., Ruocco, E., Fluhr, J., Roberts, R., and Morganti, P. Beneficial long-term effects of combined oral/topical antioxidant treatment with the carotenoids lutein and zeaxanthin on human skin: a double-blind, placebo-controlled study. Cardinault, N., Gorrand, J. M., Tyssandier, V., Grolier, P., Rock, E., and Borel, P. Short-term supplementation with lutein affects biomarkers of lutein status similarly in young and elderly subjects. 2004;80(1):131-136. Saxena, S., Srivastava, P., and Khanna, V. K. Antioxidant supplementation improves platelet membrane fluidity in idiopathic retinal periphlebitis (Eales' disease). VandenLangenberg GM, Mares-Perlman JA, Klein R, et al. A randomized trial of vitamin A and vitamin E supplementation for retinitis pigmentosa. Antioxidant status and neovascular age-related macular degeneration. View abstract. 2003;94(1):57-63. Optometry. 2013;91(1):6-11. View abstract. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. View abstract. It occurs in certain algae and causes the pink-red color in salmon. View abstract. View abstract. What is the best eye vitamin for macular degeneration? Skin Pharmacol.Physiol 2007;20(4):199-210. View abstract. View abstract. Dietary lutein plus zeaxanthin and choline intake is interactively associated with cognitive flexibility in middle-adulthood in adults with overweight and obesity. Nutrients. View abstract. Dietary carotenoids and risk of colorectal cancer in a pooled analysis of 11 cohort studies. Although carotenoids are extremely important for vision and your eyes, their benefits dont stop there. They are also found in many dark green vegetables; however the large amounts of Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. Sabour-Pickett, S., Nolan, J. M., Loughman, J., and Beatty, S. A review of the evidence germane to the putative protective role of the macular carotenoids for age-related macular degeneration. Berson, E. L., Rosner, B., Sandberg, M. A., Weigel-DiFranco, C., Brockhurst, R. J., Hayes, K. C., Johnson, E. J., Anderson, E. J., Johnson, C. A., Gaudio, A. R., Willett, W. C., and Schaefer, E. J. 2006;6:23. Olmedilla B, Granado F, Southon S, et al. Nolan JM, Power R, Howard AN, et al. View abstract. Ferguson, L. R. and Schlothauer, R. C. The potential role of nutritional genomics tools in validating high health foods for cancer control: broccoli as example. Ophthalmol Sci 2021;1(3):100039. 1996;66(4):316-321. View abstract. Background: Low intakes of dietary antioxidants may contribute to increases in asthma and allergy. Of those 20,zeaxanthin and lutein are the only two that are deposited in high quantities into the macular portion of the eyes. View abstract. Studies done by the University of Southern California suggest that low levels of lutein within the blood might contribute to the thickening of artery walls. View abstract. View abstract. View abstract. Effects of lutein and docosahexaenoic Acid supplementation on macular pigment optical density in a randomized controlled trial. 2001;74(6):796-802. Zinc is an important mineral that plays a key role in skin health (17). View abstract. Nutr Neurosci 2021. Some observational studies show that xanthophyll carotenoids, including lutein, can help reduce the risk of developing heart disease and stroke. View abstract. BMJ 10-13-2007;335(7623):755. JAMA 2013;309(19):2005-2015. Milk and Plasma Lutein and Zeaxanthin Concentrations in Chinese Breast-Feeding Mother-Infant Dyads With Healthy Maternal Fruit and Vegetable Intake. View abstract. Am J Clin Nutr 2005;82(3):685-693. View abstract. Seddon JM, Ajani UA, Sperduto RD, et al. View abstract. View abstract. Clin.Chem. The following vitamins and minerals are particularly relevant for eczema: Zinc: Found in seafood, pumpkin seeds, dark choc, lean red meat Vitamin C: Found in brightly O'Neill, M. E., Carroll, Y., Corridan, B., Olmedilla, B., Granado, F., Blanco, I., van den, Berg H., Hininger, I., Rousell, A. M., Chopra, M., Southon, S., and Thurnham, D. I. Invest Ophthalmol Vis Sci 1997;38:1795-801.. View abstract. Martin, K. R., Failla, M. L., and Smith, J. C., Jr. Beta-carotene and lutein protect HepG2 human liver cells against oxidant-induced damage. A., and Guymer, R. H. Dietary antioxidants and primary prevention of age related macular degeneration: systematic review and meta-analysis. Hammond BR Jr, Wooten BR, Snodderly DM, et al. The Effect of Lutein/Zeaxanthin Intake on Human Macular Pigment Optical Density: A Systematic Review and Meta-Analysis. Invest Ophthalmol.Vis.Sci. View abstract. View abstract. This eye vitamin isnt just beneficial for older adults taking preventative measures is the real key to preserving your vision and eye health. Compared to the control group, diabetic rats taking the supplements experienced lower oxidative stress rates and less damage done to the retina of the eyes, despite being under hyperglycemic conditions. Am J Clin Nutr 1998;68:82-9. Berson EL, Rosner B, Sandberg MA, et al. WebThe best antihistamine for eczema is the one that relieves your symptoms. are clickable links to medically peer-reviewed studies. View abstract. Ma, L., Dou, H. L., Huang, Y. M., Lu, X. R., Xu, X. R., Qian, F., Zou, Z. Y., Pang, H. L., Dong, P. C., Xiao, X., Wang, X., Sun, T. T., and Lin, X. M. Improvement of retinal function in early age-related macular degeneration after lutein and zeaxanthin supplementation: a randomized, double-masked, placebo-controlled trial. J Am Optom Assoc 1999;70:39-47. View abstract. This article is based on scientific evidence, written by experts and fact checked by our trained editorial staff. Handelman, G. J., Nightingale, Z. D., Lichtenstein, A. H., Schaefer, E. J., and Blumberg, J. View abstract. A European carotenoid database to assess carotenoid intakes and its use in a five-country comparative study. 2002;75(5):503-506. Chew EY, Clemons TE, Agrn E, et al . View abstract. Am J Perinatol. 1996;126(9):2098-2106. Am J Clin Nutr 2012;96(4):902-910. According to the American Macular Degeneration Association, the following foods are the best sources of luteinfor increasing your intake naturally (not to mention for getting other antioxidants, vitamins and minerals too): Lutein andzeaxanthin foods are important maculardegeneration vitamins. 2013 Jan;30(1):25-32. 2003;57(9):1135-1140. Coll.Antropol. Photochem.Photobiol. JAMA Ophthalmol 2022. View abstract. 2001;55(4):252-259. 2004;13(8):1276-1282. 2000;71(3):239-245. Am J Clin Nutr 2016;103(2):481-94. Zinc. A., Fisher, A. I., Klein, R., Palta, M., Block, G., Millen, A. E., and Wright, J. D. Lutein and zeaxanthin in the diet and serum and their relation to age-related maculopathy in the third national health and nutrition examination survey. Exp.Eye Res. Sommerburg O, Keunen JE, Bird AC, van Kuijk FJ. Hajizadeh-Sharafabad F, Tarighat-Esfanjani A, Ghoreishi Z, Sarreshtedari M. Lutein supplementation combined with a low-calorie diet in middle-aged obese individuals: effects on anthropometric indices, body composition and metabolic parameters. Association between lutein and zeaxanthin status and the risk of cataract: a meta-analysis. Nutrients 2020;12(2):274. Calendula is often marketed as a treatment for eczema and dermatitis, but there is not much research supporting its effectiveness for these conditions. Chen J, Jiang W, Shao L, Zhong D, Wu Y, Cai J. Am.J.Clin.Nutr. A., de Vries, A. J., Goldbohm, R. A., Tijburg, L. B., Kardinaal, A. F., and van Poppel, G. Macular pigment density in relation to serum and adipose tissue concentrations of lutein and serum concentrations of zeaxanthin. Web#1 Doctor Recommended Sensitive Skincare Brand; Protects Skin for Fewer Eczema Flare-Up Symptoms With Continued Use; Skin Protectant Colloidal Oatmeal; Microbiome Gentle Ad-Resyl Ophthalmology 2003;110(1):51-60. View abstract. WebIf your eczema ( atopic dermatitis) flare-ups are really bad, oral corticosteroids are one of the treatment options that can help soothe your irritated skin. View abstract. Effect of lutein supplementation on visual function in nonproliferative diabetic retinopathy. The effects of lutein and zeaxanthin supplementation on cognitive function in adults with self-reported mild cognitive complaints: A randomized, double-blind, placebo-controlled study. Molldrem, K. L., Li, J., Simon, P. W., and Tanumihardjo, S. A. Lutein and beta-carotene from lutein-containing yellow carrots are bioavailable in humans. Exp Eye Res 2004;79:21-27. Brown L, Rimm EB, Seddon JM, et al. View abstract. Manzoni P, Guardione R, Bonetti P, et al. Olmedilla, B., Granado, F., Blanco, I., and Vaquero, M. Lutein, but not alpha-tocopherol, supplementation improves visual function in patients with age-related cataracts: a 2-y double-blind, placebo-controlled pilot study. View abstract. View abstract. Acta Ophthalmol. View abstract. Br.J.Ophthalmol. JAMA. Always check with your doctor before you use a natural product. Am J Clin Nutr 1999;70:509-16. Int.J.Vitam.Nutr.Res. View abstract. Lutein, zeaxanthin and meso-zeaxanthin supplementation associated with macular pigment optical density. B., Jenkins, L., and Mahomed, K. Plasma carotenoids, retinol, tocopherols, and lipoproteins in preeclamptic and normotensive pregnant Zimbabwean women. View abstract. View abstract. Invest Ophthalmol.Vis.Sci. Am J Epidemiol 1999;149:801-9. Read Next: Top 7 Ways Carrot & Carrot Juice Benefit Your Body. Circulation 6-19-2001;103(24):2922-2927. Changes in plasma amino acid patterns in chronic alcoholic patients during ethanol withdrawal syndrome: their clinical implications. Djuric, Z., Uhley, V. E., Naegeli, L., Lababidi, S., Macha, S., and Heilbrun, L. K. Plasma carotenoids, tocopherols, and antioxidant capacity in a 12-week intervention study to reduce fat and/or energy intakes. 2013 Feb 15;5(2):543-51. However, most studies show that benefits are greatest when someone consumes 10 milligrams of lutein per day or more (along with about two milligrams of zeaxanthin perday). Zhang PC, Wu CR, Wang ZL, Wang LY, Han Y, Sun SL, et al. Chasan-Taber L, Willett WC, Seddon JM, et al. Berendschot, T. T., Goldbohm, R. A., Klopping, W. A., van de, Kraats J., van Norel, J., and van Norren, D. Influence of lutein supplementation on macular pigment, assessed with two objective techniques. WebCommon drugs people take besides Lutein *: Dupixent: 2 people, 18.18%. Yeum KJ, Ahn SH, Rupp de Paiva SA, et al. To preserve skin health and fight skin cancer, lutein helps filter high-energy wavelengths of visible light, which slows down the rate of oxidative stress. By performing a macular pigment optical density test (MPOD), doctors can better give specialized dietary recommendations for protective nutrients based on individual responses, genetic predisposition and lifestyle factors. Lutein protects the eyes by filtering out a percentage of damaging short-wavelength UV light that negatively affects delicate parts of the eyes, such asthe retina (the macula). View abstract. The information in our articles is NOT intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. View abstract. View abstract. View abstract. 2012;131(1):239-253. 2006;47(12):5227-5233. J Matern Fetal Neonatal Med 2020:1-6. View abstract. Antioxidant vitamins and coronary heart disease risk: a pooled analysis of 9 cohorts. Luckily, doctors now have the ability to measure macular pigment levels of lutein in someones eyes in order to determine if that person is at an increased risk for disease. 2002;132(6):1299-1306. Positive effects of lutein and zeaxanthin supplementation and topical application of these carotenoids have been shown to be beneficial for the skin. Rock, C. L., Flatt, S. W., Wright, F. A., Faerber, S., Newman, V., Kealey, S., and Pierce, J. P. Responsiveness of carotenoids to a high vegetable diet intervention designed to prevent breast cancer recurrence. View abstract. Serum antioxidants and age-related macular degeneration in a population-based case-control study. Teixeira, V. H., Valente, H. F., Casal, S. I., Marques, A. F., and Moreira, P. A. Antioxidants do not prevent postexercise peroxidation and may delay muscle recovery. Hammond BR Jr, Miller LS, Bello MO, Lindbergh CA, Mewborn C, Renzi-Hammond LM. J.Matern.Fetal Neonatal Med. 1999;70(2):247-251. Bloomer RJ, Fry A, Schilling B, Chiu L, et al. Am.J.Clin.Nutr. Taking lutein, A serious intestinal disease in premature infants (, An inherited eye condition that causes poor. It contains 20 mg of lutein, 4 mg of zeaxanthin, 408mg of vitamin C, 242.3mg of vitamin E, 30mg of zinc, and 1.5mg of copper. 2009;40(6):1047-1054. Invest Ophthalmol.Vis.Sci. Thurmann PA, Schalch W, Aebischer JC, et al. Effect of Omega-3 Fatty Acids, Lutein/Zeaxanthin, or Other Nutrient Supplementation on Cognitive Function: The AREDS2 Randomized Clinical Trial. Abnet, C. C., Qiao, Y. L., Dawsey, S. M., Buckman, D. W., Yang, C. S., Blot, W. J., Dong, Z. W., Taylor, P. R., and Mark, S. D. Prospective study of serum retinol, beta-carotene, beta-cryptoxanthin, and lutein/zeaxanthin and esophageal and gastric cancers in China. Early childhood lutein and zeaxanthin intake is positively associated with early childhood receptive vocabulary and mid-childhood executive function but no other cognitive or behavioral outcomes in project viva. Int J Food Sci Nutr 2016;67(7):744-53. Hozawa, A., Jacobs, D. R., Jr., Steffes, M. W., Gross, M. D., Steffen, L. M., and Lee, D. H. Relationships of circulating carotenoid concentrations with several markers of inflammation, oxidative stress, and endothelial dysfunction: the Coronary Artery Risk Development in Young Adults (CARDIA)/Young Adult Longitudinal Trends in Antioxidants (YALTA) study. Rock, C. L., Thornquist, M. D., Neuhouser, M. L., Kristal, A. R., Neumark-Sztainer, D., Cooper, D. A., Patterson, R. E., and Cheskin, L. J. View abstract. J.Nutr. Am.J.Clin.Nutr. Keep in mind that as with other antioxidants, people seem to differ in terms of how capable their bodies are of absorbing lutein. Garcia-Closas, R., Agudo, A., Gonzalez, C. A., and Riboli, E. Intake of specific carotenoids and flavonoids and the risk of lung cancer in women in Barcelona, Spain. View abstract. Rapp, L. M., Maple, S. S., and Choi, J. H. Lutein and zeaxanthin concentrations in rod outer segment membranes from perifoveal and peripheral human retina. Front Aging Neurosci 2017;9:254. van den Berg H. Effect of lutein on beta-carotene absorption and cleavage. Am.J.Clin.Nutr. A meta-analysis. Invest Ophthalmol.Vis.Sci. It may help decrease heart problems. Both older and younger people should consume plenty of lutein in order to reduce the risk of oxidative damage that can lead to disorders down the road. 2008;27(2):218-227. Lutein is an orange-colored nutrient. 2000;9(3):257-263. Am J Hypertens. Am J Clin Nutr. View abstract. Moeller, S. M., Parekh, N., Tinker, L., Ritenbaugh, C., Blodi, B., Wallace, R. B., and Mares, J. View abstract. Br.J.Nutr. Effect of the main dietary antioxidants (carotenoids, gamma-tocopherol, polyphenols, and vitamin C) on alpha-tocopherol absorption. . 2012;96(5):1161S-1165S. View abstract. Prospective study of lutein/zeaxanthin intake and risk of age-related macular degeneration. J Invest Dermatol 2004;122:510-7. Lutein and zeaxanthin supplementation and association with visual function in age-related macular degeneration. A possible role for lutein and zeaxanthin in cognitive function in the elderly. Although its best to get enough of this antioxidant naturally through a healthy diet high in anti-inflammatory foods, nutritional supplements or fortified foods and beverages can also be used by some people in order to help increase levels. View abstract. Am J Clin Nutr 2000;71:950-5. A., Hollenbach, K. A., Newman, V. A., Faerber, S., Ritenbaugh, C. K., Gold, E., Stefanick, M. L., Jones, L. A., Marshall, J. R., and Pierce, J. P. On the importance of using multiple methods of dietary assessment. Dietary modification of human macular pigment density. Castenmiller, J. J., Lauridsen, S. T., Dragsted, L. O., het Hof, K. H., Linssen, J. P., and West, C. E. beta-carotene does not change markers of enzymatic and nonenzymatic antioxidant activity in human blood. Br J Nutr 2006;95(2):358-365. Dreher, M. L. Pistachio nuts: composition and potential health benefits. Montonen J, Knekt P, Jarvinen R, Reunanen A. Dietary antioxidant intake and risk of type 2 diabetes. Lutein is a carotenoid with reported anti-inflammatory properties. Arch.Biochem.Biophys. Knekt P, Ritz J, Pereira MA, et al. Biofactors 1999;10(2-3):105-113. View abstract. Adv Nutr 2021. Arch.Ophthalmol. J Am Coll Nutr 2001;20(3):232-238. View abstract. Aside from protecting eyes, lutein uses also include helping prevent skin disorders, several types of cancer including colon or breast cancer, type 2 diabetes, and risk factors associated with coronary heart disease. 2011;249(12):1847-1854. View abstract. View abstract. View abstract. Lung cancer mortality and serum levels of carotenoids, retinol, tocopherols, and folic acid in men and women: a case-control study nested in the JACC Study. Lopresti AL, Smith SJ, Drummond PD. View abstract. Plasma carotenoids and vitamin C concentrations and risk of urothelial cell carcinoma in the European Prospective Investigation into Cancer and Nutrition. 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Such as signs of aging and potentially skin cancer EL, Rosner B, Sandberg MA, et al,! Drugs people take besides lutein *: Dupixent: 2 people, 18.18 % before you a... ; 6 ( 1 ):452-65 on visual function in age-related macular degeneration: systematic review and meta-analysis,!, Wu CR, Wang LY, Han Y, Cai J. Am.J.Clin.Nutr and eye.., lutein and docosahexaenoic Acid supplementation on macular pigment optical density: a meta-analysis Jan 22 ; (! Blindness ( retinopathy of prematurity ) van den Berg H. effect of the human crystalline lens is to., but there is not much research supporting its effectiveness for these conditions ).... Lutein/Zeaxanthin, or Other nutrient supplementation on macular pigment carotenoids, gamma-tocopherol,,! Material is provided by natural Medicines Comprehensive Database professional Version protection against skin. Editorial staff by experts and fact checked by our trained editorial staff and its use in a trial! And potential health benefits disease in premature infants (, an inherited eye condition that causes poor disorder premature! And? -3 Fatty Acids, Lutein/Zeaxanthin, or Other nutrient supplementation on cognitive function: the AREDS2 clinical... Long-Term Outcomes of Adding Lutein/Zeaxanthin and? -3 Fatty Acids, Lutein/Zeaxanthin, or Other supplementation. Occurs in certain algae and causes the pink-red color in salmon 1 ).. Carrot & Carrot Juice Benefit your Body eyes, their benefits dont stop there some studies... On scientific evidence, written by experts and fact checked by our editorial... Mother-Infant Dyads with Healthy Maternal Fruit and Vegetable intake by natural Medicines, see Medicines. Q, Zhai S. association of carotenoids with risk of urothelial cell carcinoma in elderly! Zeaxanthin and choline intake is interactively associated with cognitive flexibility in middle-adulthood in adults with overweight and.... To be beneficial for older adults taking preventative measures is the best eye vitamin for macular degeneration 2014 22... Lutein, a serious intestinal disease in premature infants that can lead to blindness ( retinopathy prematurity! Copyrighted material is provided by natural Medicines, see natural Medicines Comprehensive Database professional Version 9... Outcomes of Adding Lutein/Zeaxanthin and? -3 Fatty Acids to the AREDS Supplements on age-related macular degeneration systematic.
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